Archive: 2026/01
Tricyclic Antidepressants and Antihistamines: Why Combining Them Can Cause Anticholinergic Overload
Combining tricyclic antidepressants like amitriptyline with antihistamines like Benadryl can cause dangerous anticholinergic overload, leading to confusion, delirium, and increased dementia risk. Learn how to spot and prevent this hidden danger.
Population Pharmacokinetics: Using Real-World Data to Prove Drug Equivalence
Population pharmacokinetics uses real-world patient data to prove drug equivalence across diverse populations, offering a powerful alternative to traditional bioequivalence studies-especially for complex cases like pediatric, elderly, or renal-impaired patients.
Grapefruit Juice and Simvastatin: What You Need to Know About Myopathy and Toxicity Risk
Grapefruit juice can dangerously increase simvastatin levels, raising the risk of muscle damage and kidney failure. Learn how much is unsafe, which statins are safer, and what to do if you're on this medication.
How to Prevent Wrong-Dose Errors with Liquid Medications: A Practical Guide for Patients and Providers
Learn how to prevent dangerous wrong-dose errors with liquid medications using oral syringes, mL-only measurements, and proven safety practices for home and healthcare settings.
Online Pharmacies and Generics: How to Spot Safe vs. Dangerous Sites
Online pharmacies offer cheap generics, but 82% are unsafe. Learn how to spot legitimate sites, avoid counterfeit drugs, and protect your health with simple verification steps.
Rheumatoid Arthritis Monitoring: CDAI, DAS28, and Imaging Explained
Learn how CDAI, DAS28, and imaging tools like ultrasound and MRI help track rheumatoid arthritis activity, predict joint damage, and guide treatment decisions for better long-term outcomes.
Fluoroquinolone Antibiotics and NSAIDs: Why Combining Them Raises Serious Neurologic and Kidney Risks
Combining fluoroquinolone antibiotics with NSAIDs raises the risk of severe kidney injury and long-term neurological damage. Learn who’s most at risk and what safer alternatives exist.
Managing Therapeutic Equivalents in Combination Products: Dose Differences and Real-World Risks
Managing therapeutic equivalence in combination drugs isn't just about matching labels. Dose differences, formulation changes, and NTI drugs create hidden risks. Learn how to avoid dangerous substitutions and protect patient safety.
How to Prepare for and Ask the Right Questions About Medications with Your OB/GYN
Learn how to prepare for your OB/GYN visit with a complete medication list, ask the right questions about pregnancy and breastfeeding safety, and avoid common mistakes that put you and your baby at risk.
Pharmacy Inventory Management: Effective Generic Stocking Strategies for 2026
Learn how to optimize generic drug inventory in pharmacies using data-driven strategies, reorder points, and real-world systems. Reduce costs, avoid stockouts, and improve cash flow with practical 2026-ready techniques.
Crossover Trial Design: How Bioequivalence Studies Are Structured
Crossover trial design is the gold standard for bioequivalence studies, allowing each participant to serve as their own control. This reduces sample size, improves accuracy, and meets global regulatory requirements for generic drug approval.
Generic combination products: When multiple generics equal one brand
Generic combination products combine drugs and devices, but substitution rules haven’t kept up. Learn why swapping generics for branded combos like EpiPen isn’t simple-and how new FDA rules are trying to fix it.